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S-Fer Syrup

Sodium Feredetate Trihydrate
27.5 mg/5 ml
Navana Pharmaceuticals Ltd.
Pack size 100 ml bottle
Price 100.00 BDT

Indications

S-Fer Syrup is used for: Iron-deficiency anaemia

Adult Dose

Adults: 5 mL 3 times a day, increased to 10 mL 3 times a day, dose to be increased gradually

Child Dose

Children/Infants: 3-6 mg/kg elemental iron daily divided into 2-3 doses. 6-24 months ~12.5 mg/day; 2-5 years ~20-30 mg/day; 6-11 years ~30-60 mg/day. Child 1–11 months: Up to 2.5 mL twice daily, smaller doses to be used initially Child 1–4 years: 2.5 mL 3 times a day Child 5–11 years: 5 mL 3 times a day Child 12–17 years: 5 mL 3 times a day, increased to 10 mL 3 times a day, dose to be increased gradually

Renal Dose

Administration

Contra Indications

Hypersensitivity to active substance/excipients; iron‐overload states (haemochromatosis, haemosiderosis); repeated blood transfusions.

Precautions

In patients with haemolytic anaemia or disorders of iron‐absorption/storage. Iron preparations may colour stools black and may interfere with occult blood testing. Avoid concurrent administration with milk/dairy products or other inhibitors of iron absorption.

Pregnancy-Lactation

Pregnancy and Lactation: No specific adverse events reported in pregnancy/lactation in certain datasets; however, use as per iron?deficiency status.

Interactions

Iron absorption reduced by antacids, calcium, magnesium, zinc, tetracyclines, bisphosphonates, dairy, tea, eggs. Iron may reduce absorption of penicillamine, mycophenolate, fluoroquinolones, levodopa/carbidopa, bisphosphonates.

Adverse Effects

Side effects of Sodium Feredetate Trihydrate : Common: gastrointestinal upset (nausea, vomiting, diarrhoea, constipation, flatulence). Rare: hypersensitivity (rash, swelling).

Mechanism of Action

Provides a bioavailable iron source—the iron is chelated with EDTA to enhance solubility and absorption even in presence of dietary inhibitors. Once absorbed, iron is incorporated into haemoglobin and stored as ferritin/haemosiderin.

Note

S-Fer 27.5 mg/5 ml Syrup manufactured by Navana Pharmaceuticals Ltd.. Its generic name is Sodium Feredetate Trihydrate. S-Fer is availble in Bangladesh. DIMS information on S-Fer Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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