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Herplex Eye Drops

Idoxuridine 0.1% Eye prep
1 mg/ml
OSL Pharma Limited.
Pack size 10 ml drop
Price 60.20 BDT

Indications

Herplex Eye Drops is used for: Herpes simplex keratitis

Adult Dose

Ophthalmic Herpes simplex keratitis Adult: As 0.1% soln: Instill 1 drop in the affected eye(s) every hr. Taper to every 2 hr or 4 times daily. Continue treatment for at least 7 days.

Child Dose

Renal Dose

Administration

Contra Indications

Hypersensitivity.

Precautions

Deep ulceration of the stromal layers of the cornea. Avoid prolonged use. Pregnancy and lactation.

Pregnancy-Lactation

Interactions

Corticosteroids may accelerate spread of viral infection.

Adverse Effects

Side effects of Idoxuridine 0.1% Eye prep : Ophthalmic: Irritation; inflammation of the eye or eyelids; pain; photophobia; pruritus; conjunctivitis; oedema. Rarely, lachrymal duct occlusion and hypersensitivity reactions. Corneal damage (prolonged use).

Mechanism of Action

Idoxuridine, a pyrimidine nucleoside structurally related to thymidine, inhibits viral replication by substituting itself for thymidine in viral DNA. It is active against herpes simplex and varicella zoster viruses, and has also been shown to inhibit vaccinia virus, cytomegalovirus and adenovirus.

Note

Herplex 1 mg/ml Eye Drops manufactured by OSL Pharma Limited.. Its generic name is Idoxuridine 0.1% Eye prep. Herplex is availble in Bangladesh. DIMS information on Herplex Eye Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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