A B1

Tablet

100mg

Thiamine Hydrochloride

Acme Laboratories Ltd.

Unit Price: 0.86 BDT

Packsize: 100'pack

Precaution

Parenteral admin. Increased daily requirements in pregnancy and lactation.

Indication

Beriberi and Wernick's encephalopathy, neuritis associated with pregnancy and pellagra.

Adult Dose

Treatment and prophylaxis of mild chronic thiamine deficiency Adult: 10-25 mg daily in single or divided doses. Thiamine deficiency Adult: 1 tablet (100mg) daily, up to 300 mg daily. Wernicke-Korsakoff syndrome Adult: Initially, 100 mg by slow IV Inj over 10 min, then 50-100 mg/day IM or IV until the patient can take oral thiamine.

Child Dose

Thiamine deficiency 10-50 mg/day PO in divided doses Beriberi 10-25 mg IV/IM qDay (if crtically ill) or 10-50 mg/dose PO qDay for at least 2 weeks, THEN 5-10 mg/day PO for 1 month

Administration

Should be taken with food.

Side Effect

IV: Warm sensation, tingling, pruritus, pain, urticaria, weakness, sweating, nausea, restlessness, tightness of the throat, angioedema, respiratory distress, cyanosis, pulmonary oedema, GI bleeding, transient vasodilation and hypotension, vascular collapse. IM: Tenderness and induration. Potentially Fatal: Very rarely, fatal anaphylactic shock.

Pregnancy Category

Pregnancy Category: A (injectable); C (if >RDA) Lactation: Safe

Interaction

May enhance the effect of neuromuscular blocking agents.